A multicleanse TrizEDTA solution. For use in dogs and cats as a cleaning and/or alkalinizing and/or pretreatment solution. Can be used without other meds or if used with antibiotic ear meds apply 1/2 hour before the antibacterial medication is applied. Aids in breakdown of inflammatory discharge in ears with more effective use of the antibiotic used for treating the infection. Tris-EDTA buffer solutions are valuable as a long-term therapy for preventing the recurrence of Pseudomonas infection, either as part of a regular ear cleaning regimen or as a presoak before placing antibacterial solution into the ear canal. Such solutions are typically applied two to three times per week as needed.